Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950394 | 0.92 | MEN1 (0.56) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3947142 | 0.92 | MEN1 (0.53) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3942576 | 0.90 | PKM (0.52) | — | |
| SCHEMBL13942611 | 0.89 | MEN1 (0.51) | MEN1KMT2AALDH1A1 | |
| SCHEMBL13942605 | 0.89 | TSHR (0.52) | RXFP1MEN1KMT2AALDH1A1 | |
| SCHEMBL3946511 | 0.89 | MEN1 (0.61) | RXFP1MEN1KMT2A | |
| SCHEMBL3942341 | 0.89 | MEN1 (0.65) | RXFP1MEN1KMT2A | |
| SCHEMBL3944971 | 0.87 | MEN1 (0.48) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3949873 | 0.87 | MEN1 (0.62) | RXFP1MEN1KMT2A | |
| SCHEMBL3943539 | 0.86 | GAA (0.54) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |