Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3951595 | 0.89 | GAA (0.54) | GAATSHRBLMPKMHTT | |
| SCHEMBL3943138 | 0.86 | RXFP1 (0.55) | MEN1KMT2A | |
| SCHEMBL13942605 | 0.86 | TSHR (0.52) | TSHRPKMHTTMEN1KMT2A | |
| SCHEMBL3942883 | 0.86 | TSHR (0.55) | GAATSHRBLMPKMHTT | |
| SCHEMBL3942576 | 0.86 | PKM (0.52) | PKM | |
| SCHEMBL3950394 | 0.85 | MEN1 (0.56) | TSHRPKMHTTMEN1KMT2A | |
| SCHEMBL3947142 | 0.85 | MEN1 (0.53) | TSHRPKMMEN1KMT2ATP53 | |
| SCHEMBL3944408 | 0.83 | TSHR (0.49) | GAATSHRBLMPKMHTT | |
| SCHEMBL13942611 | 0.83 | MEN1 (0.51) | TSHRMEN1KMT2ATP53 | |
| SCHEMBL3944971 | 0.83 | MEN1 (0.48) | GAATSHRBLMHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |