Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950394 | 0.96 | MEN1 (0.56) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL13942605 | 0.93 | TSHR (0.52) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL13942611 | 0.93 | MEN1 (0.51) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL3943138 | 0.92 | RXFP1 (0.55) | MEN1KMT2AALDH1A1 | |
| SCHEMBL13942609 | 0.91 | PKM (0.52) | MEN1KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL13942363 | 0.90 | ADORA2B (0.55) | MEN1KMT2A | |
| SCHEMBL3942576 | 0.89 | PKM (0.52) | PKM | |
| SCHEMBL3944408 | 0.86 | TSHR (0.49) | TP53TSHRPKM | |
| SCHEMBL3944871 | 0.86 | HTT (0.44) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL3944971 | 0.86 | MEN1 (0.48) | MEN1KMT2AKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |