Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952225 | 0.94 | ALDH1A1 (0.44) | EPHX2CD274ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3953107 | 0.93 | ALDH1A1 (0.43) | EPHX2CD274ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3941985 | 0.93 | ALDH1A1 (0.46) | EPHX2CD274ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3944682 | 0.92 | ALDH1A1 (0.43) | EPHX2CD274ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3949764 | 0.92 | L3MBTL1 (0.43) | EPHX2CD274ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3950137 | 0.91 | CD274 (0.43) | EPHX2CD274ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3951132 | 0.91 | ALDH1A1 (0.42) | EPHX2CD274ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3943388 | 0.90 | ALDH1A1 (0.41) | EPHX2CD274ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3946197 | 0.90 | ALDH1A1 (0.42) | EPHX2CD274ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3940688 | 0.90 | ALDH1A1 (0.45) | EPHX2ALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802572-B1 | INDOL DERIVATIVES AS INHIBITORS OF SOLUBLE ADENYLYL CYCLASE | BAYER SCHERING PHARMA AG (DE) | 2009-04-22 | — | — | EP | claimed |
| EP-1802572-B1 | INDOL DERIVATIVES AS INHIBITORS OF SOLUBLE ADENYLYL CYCLASE | BAYER SCHERING PHARMA AG (DE) | 2009-04-22 | — | — | EP | disclosed |