Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954707 | 0.86 | TDP1 (0.32) | — | |
| SCHEMBL3948722 | 0.83 | AGTR2 (0.35) | ACHELMNANT5EAGTR2PTPN1 | |
| SCHEMBL3949496 | 0.83 | PPM1D (0.31) | — | |
| SCHEMBL3944118 | 0.81 | TRPM8 (0.35) | ACHETAAR1LMNANT5EAGTR2 | |
| SCHEMBL3954243 | 0.81 | — | — | |
| SCHEMBL3948575 | 0.78 | PPM1D (0.31) | — | |
| SCHEMBL3949518 | 0.78 | — | — | |
| SCHEMBL3947145 | 0.77 | MAPT (0.34) | — | |
| SCHEMBL3954716 | 0.77 | — | — | |
| SCHEMBL3944056 | 0.76 | CAPN1 (0.33) | ACHEAGTR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |