Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944118 | 0.88 | TRPM8 (0.35) | AGTR2ACHELMNAEPHX2NT5E | |
| SCHEMBL3944079 | 0.83 | ACHE (0.33) | AGTR2ACHELMNAEPHX2NT5E | |
| SCHEMBL3944056 | 0.83 | CAPN1 (0.33) | AGTR2ACHEEPHX2CHRM3DPP4 | |
| SCHEMBL2496847 | 0.79 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL3949961 | 0.78 | LMNA (0.33) | LMNA | |
| SCHEMBL3954955 | 0.76 | PKM (0.36) | LMNAALDH1A1MEN1GAAKMT2A | |
| SCHEMBL3952247 | 0.71 | FFAR4 (0.33) | MEN1KMT2ACHRM3 | |
| SCHEMBL7309273 | 0.69 | SMN1; SMN2 (0.40) | ALDH1A1TSHRKMT2A | |
| SCHEMBL3948771 | 0.69 | LMNA (0.33) | LMNA | |
| SCHEMBL19714859 | 0.67 | CNR2 (0.42) | AGTR2LMNAALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |