Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2794197 | 0.77 | LMNA (0.36) | — | |
| SCHEMBL3468690 | 0.75 | HTR2A (0.35) | DUT | |
| SCHEMBL14659044 | 0.74 | KDM4E (0.35) | DUT | |
| SCHEMBL30189828 | 0.74 | KDM4E (0.35) | DUT | |
| SCHEMBL21395337 | 0.74 | BACE1 (0.33) | — | |
| SCHEMBL23883039 | 0.72 | EPHX2 (0.39) | DUT | |
| SCHEMBL2794203 | 0.71 | TLR7 (0.42) | — | |
| SCHEMBL19782769 | 0.71 | CA12 (0.39) | DUT | |
| SCHEMBL23245930 | 0.71 | DHFR (0.38) | — | |
| SCHEMBL6114675 | 0.70 | DUT (0.34) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831198-B1 | PYRIDINE CARBOXAMIDE DERIVATIVES FOR USE AS ANTICANCER AGENTS | ASTRAZENECA AB (SE) | 2009-04-08 | — | — | EP | disclosed |