SCHEMBL2274342

SCHEMBL2274342

O=C1CCCCCCC(=O)[C@@H](C(=O)O)N1

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.33
MCL1 Q07820 1/20 0.33
CAD P27708 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FKBP5 Q13451 1/20 0.32
CRBN Q96SW2 1/20 0.32
GRIA2 P42262 1/20 0.32
MME P08473 5/20 0.31
ACE P12821 3/20 0.31
ITGB3 P05106 1/20 0.31
ITGB2 P05107 1/20 0.31
ITGB1 P05556 1/20 0.31
ITGAV P06756 1/20 0.31
ITGA2B P08514 1/20 0.31
ITGA5 P08648 1/20 0.31
ITGB5 P18084 1/20 0.31
ITGAL P20701 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL380941 1.00 KMT2A (0.33) KMT2AMCL1CADALDH1A1MAPT
SCHEMBL9699920 1.00 KMT2A (0.33) KMT2AMCL1CADALDH1A1MAPT
SCHEMBL9699954 1.00 KMT2A (0.33) KMT2AMCL1CADALDH1A1MAPT
SCHEMBL9699985 0.98 MCL1 (0.34) KMT2AMCL1CADALDH1A1MAPT
SCHEMBL737201 0.85 ITGB3 (0.34) CADCRBNGRIA2ITGB3ITGB2
SCHEMBL9172323 0.82 CRBN (0.33) KMT2AMCL1ALDH1A1MAPTL3MBTL1
SCHEMBL4224698 0.74 ITGB3 (0.35) CADGRIA2ITGB3ITGB2ITGB1
SCHEMBL8563469 0.74 ITGB3 (0.35) CADGRIA2ITGB3ITGB2ITGB1
SCHEMBL1891354 0.73 CAD (0.39) KMT2AMCL1CADMMEACE
SCHEMBL1891532 0.73 CAD (0.39) KMT2AMCL1CADMMEACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12385916-B2 Serum metabolic biomarkers and kit for detecting drug-resistant tuberculosis Zhejiang SUKEAN Pharmaceutical Co., Ltd. (CN) 2025-08-12 US claimed
US-12196753-B2 Kit for detecting drug-resistant tuberculosis Zhejiang SUKEAN Pharmaceutical Co., Ltd. (CN) 2025-01-14 US claimed
US-20240295555-A1 KIT FOR DETECTING DRUG-RESISTANT TUBERCULOSIS Zhejiang SUKEAN Pharmaceutical Co., Ltd. (CN) 2024-09-05 US claimed
US-12050228-B2 Automated sample quality assessment METABOLON, INC. (US) 2024-07-30 US claimed
US-20230349900-A1 SERUM METABOLIC BIOMARKERS AND KIT FOR DETECTING DRUG-RESISTANT TUBERCULOSIS Zhejiang SUKEAN Pharmaceutical Co., Ltd. (CN) 2023-11-02 US claimed
US-20210088539-A1 AUTOMATED SAMPLE QUALITY ASSESSMENT METABOLON, INC. 2021-03-25 US claimed
US-10890592-B2 Automated sample quality assessment METABOLON, INC. (US) 2021-01-12 US claimed
WO-2017189528-A1 CORROSION INHIBITOR COMPOSITIONS AND METHODS OF USING SAME Ecolab USA, Inc. (US) 2017-11-02 WO claimed
US-20170306504-A1 CORROSION INHIBITOR COMPOSITIONS AND METHODS OF USING SAME CHAMPIONX LLC 2017-10-26 US claimed
US-12591974-B2 Methods, devices, and systems for detecting analyte levels OOVA, INC. (US) 2026-03-31 US disclosed
US-12385916-B2 Serum metabolic biomarkers and kit for detecting drug-resistant tuberculosis Zhejiang SUKEAN Pharmaceutical Co., Ltd. (CN) 2025-08-12 US disclosed
US-12385916-B2 Serum metabolic biomarkers and kit for detecting drug-resistant tuberculosis Zhejiang SUKEAN Pharmaceutical Co., Ltd. (CN) 2025-08-12 US disclosed
US-12329726-B2 Biomarkers for efficacy of prophylactic treatments against stress-induced affective disorders THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-06-17 US disclosed
US-12259397-B2 Biomarkers related to organ function University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2025-03-25 US disclosed
EP-0979306-A4 AN ASSAY FOR THE MEASUREMENT OF DNA SYNTHESIS RATES UNIV GEORGE WASHINGTON (US) 2004-09-01 EP disclosed
US-6355416-B1 A NONRADIOACTIVE TRACER METHOD TO DETERMINE DNA SYNTHESIS BY ADMINISTERING STABLE ISOTOPE LABELLED PRECURSORS TO A SAMPLE THAT CONTAINS REPLICATING DNA WHICH IS INCORPORATED BY METABOLIC SALVAGE PATHWAY; DETECT THE ISOTOPE BY SPECTROMETER THE GEORGE WASHINGTON UNIVERSITY 2002-03-12 US disclosed
EP-0979306-A1 AN ASSAY FOR THE MEASUREMENT OF DNA SYNTHESIS RATES GEORGE WASHINGTON UNIVERSITY (US) 2000-02-16 EP disclosed
WO-1998036095-A1 AN ASSAY FOR THE MEASUREMENT OF DNA SYNTHESIS RATES GEORGE WASHINGTON UNIVERSITY (US) 1998-08-20 WO disclosed
US-5686491-A CARNITINE SIGMA-TAU PHARMACEUTICALS, INC. (US) 1997-11-11 US disclosed
EP-0569393-B1 DERIVATIVES OF DICARBOXYLIC ACIDS HAVING SIX TO TWELVE CARBON ATOMS AND USE OF THESE DERIVATIVES AND DICARBOXYLIC ACIDS ALONE IN THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR ENTERAL AND PARENTERAL NUTRITION PINAROO LTD (IE) 1995-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12591974-B2 Methods, devices, and systems for detecting analyte levels SHBG, GNRHR, LHCGR KMT2A 3206/4885MCL1 2508/4885CAD 1516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.