Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699954 | 0.98 | KMT2A (0.33) | MCL1CRBNL3MBTL1ALDH1A1MAPT | |
| SCHEMBL9699920 | 0.98 | KMT2A (0.33) | MCL1CRBNL3MBTL1ALDH1A1MAPT | |
| SCHEMBL380941 | 0.98 | KMT2A (0.33) | MCL1CRBNL3MBTL1ALDH1A1MAPT | |
| SCHEMBL2274342 | 0.98 | KMT2A (0.33) | MCL1CRBNL3MBTL1ALDH1A1MAPT | |
| SCHEMBL737201 | 0.87 | ITGB3 (0.34) | CRBNGRIA2ITGB3ITGB2ITGB1 | |
| SCHEMBL9172323 | 0.83 | CRBN (0.33) | MCL1CRBNL3MBTL1ALDH1A1MAPT | |
| SCHEMBL8563469 | 0.76 | ITGB3 (0.35) | GRIA2ITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL4224698 | 0.76 | ITGB3 (0.35) | GRIA2ITGB3ITGB2ITGB1ITGAV | |
| SCHEMBL6641445 | 0.72 | GRIA2 (0.44) | GRIA2KMT2A | |
| SCHEMBL1849832 | 0.72 | GRIA2 (0.44) | GRIA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483429-A1 | Biodegradable polymer compositions | NOVA PHARMACEUTICAL CORPORATION (US) | 1992-05-06 | — | — | EP | disclosed |
| US-4999417-A | Drug carriers for controlled release | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-03-12 | — | — | US | disclosed |