Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950693 | 0.93 | MMP1 (0.42) | MMP1MMP2MMP9MMP12LMNA | |
| SCHEMBL3952520 | 0.91 | RXFP1 (0.53) | RXFP1MEN1LMNATSHRHTT | |
| SCHEMBL3952068 | 0.85 | MEN1 (0.48) | RXFP1MEN1LMNAKMT2A | |
| SCHEMBL4521555 | 0.85 | RXFP1 (0.59) | RXFP1MEN1LMNATSHRHTT | |
| SCHEMBL3944160 | 0.84 | PKM (0.54) | RXFP1PKM | |
| SCHEMBL3947411 | 0.84 | MEN1 (0.50) | MEN1KMT2APKM | |
| SCHEMBL3950746 | 0.83 | RXFP1 (0.49) | RXFP1MEN1LMNAKMT2APKM | |
| SCHEMBL3949157 | 0.83 | RXFP1 (0.53) | RXFP1MEN1LMNATSHRHTT | |
| SCHEMBL3941781 | 0.83 | TP53 (0.47) | PKM | |
| SCHEMBL3945382 | 0.83 | TP53 (0.46) | MMP1MMP2MMP9MMP12PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |