Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480524 | 1.00 | LMNA (0.33) | LMNAGAA | |
| SCHEMBL3480519 | 1.00 | LMNA (0.33) | LMNAGAA | |
| SCHEMBL3480406 | 0.84 | LMNA (0.34) | LMNAGAA | |
| SCHEMBL3480405 | 0.84 | LMNA (0.34) | LMNAGAA | |
| SCHEMBL3480139 | 0.81 | LMNA (0.33) | LMNAGAA | |
| SCHEMBL3480136 | 0.81 | LMNA (0.33) | LMNAGAA | |
| SCHEMBL3480804 | 0.78 | CA2 (0.41) | — | |
| SCHEMBL3946184 | 0.75 | MMP13 (0.35) | LMNAGAA | |
| SCHEMBL3483346 | 0.75 | SNCA (0.47) | LMNAGAA | |
| SCHEMBL3483345 | 0.75 | SNCA (0.47) | LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049200-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | MethylGene Inc. (CA) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008073142-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | MERCK & CO., INC. (US) | 2008-06-19 | — | — | WO | disclosed |