Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946640 | 0.89 | CTDSP1 (0.48) | CTDSP1MAPK1HSD17B10L3MBTL1 | |
| SCHEMBL3943277 | 0.88 | CTDSP1 (0.43) | CTDSP1MAPK1HSD17B10TDP1MAOB | |
| SCHEMBL3942453 | 0.87 | CTDSP1 (0.49) | CTDSP1MAPK1HSD17B10MEN1KMT2A | |
| SCHEMBL4101784 | 0.86 | LMNA (0.45) | CTDSP1HTTSMN1; SMN2LMNATSHR | |
| SCHEMBL3940676 | 0.84 | HTT (0.40) | CTDSP1MAPK1HTTSMN1; SMN2LMNA | |
| SCHEMBL3945150 | 0.83 | CTDSP1 (0.43) | CTDSP1MAPK1HSD17B10MAOBTSHR | |
| SCHEMBL3947163 | 0.83 | LMNA (0.40) | HTTMEN1LMNATSHRKMT2A | |
| SCHEMBL3950666 | 0.81 | LMNA (0.44) | MAPK1HTTSMN1; SMN2MEN1LMNA | |
| SCHEMBL3944723 | 0.80 | SMN1; SMN2 (0.40) | MAPK1TDP1HTTSMN1; SMN2MEN1 | |
| SCHEMBL3941659 | 0.80 | HTT (0.49) | MAPK1HTTSMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |