Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940676 | 0.92 | HTT (0.40) | LMNAGAATSHRBLMCTDSP1 | |
| SCHEMBL3950666 | 0.90 | LMNA (0.44) | LMNAGAATSHRBLMHTT | |
| SCHEMBL3944456 | 0.88 | GAA (0.49) | LMNAGAATSHRBLMCTDSP1 | |
| SCHEMBL3943108 | 0.87 | GAA (0.44) | LMNAGAATSHRBLMCTDSP1 | |
| SCHEMBL3950421 | 0.86 | GAA (0.49) | GAATSHRBLMCTDSP1PKM | |
| SCHEMBL3947163 | 0.86 | LMNA (0.40) | LMNAGAATSHRBLMHTT | |
| SCHEMBL3946046 | 0.86 | CTDSP1 (0.43) | LMNATSHRCTDSP1HTTKDM4E | |
| SCHEMBL3944723 | 0.84 | SMN1; SMN2 (0.40) | LMNATSHRHTTKMT2AALDH1A1 | |
| SCHEMBL13942589 | 0.83 | TSHR (0.45) | LMNAGAATSHRHTTKDM4E | |
| SCHEMBL3942061 | 0.83 | TSHR (0.45) | LMNAGAATSHRHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |