SCHEMBL394630

SCHEMBL394630

Cc1cc2ccc(N)cc2[nH]1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.70
KEAP1 Q14145 1/20 0.70
KDM4E B2RXH2 8/20 0.44
MAPT P10636 8/20 0.44
MEN1 O00255 6/20 0.44
KMT2A Q03164 6/20 0.44
PKM P14618 3/20 0.44
HTT P42858 2/20 0.44
HRH4 Q9H3N8 1/20 0.43
EGFR P00533 1/20 0.41
AXL P30530 1/20 0.41
ALDH1A1 P00352 7/20 0.40
GAA P10253 5/20 0.40
POLB P06746 4/20 0.40
GLA P06280 4/20 0.40
RXFP1 Q9HBX9 3/20 0.40
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
GFER P55789 3/20 0.40
CACNA1B Q00975 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL7354290 0.98 CYP2A6 (0.68) CYP2A6KEAP1KDM4EMAPTMEN1
SCHEMBL397246 0.83 CYP2A6 (1.00) CYP2A6KEAP1KDM4EMAPTMEN1
Hydrochloric Acid SCHEMBL11614276 0.81 CYP2A6 (0.96) CYP2A6KEAP1KDM4EMAPTMEN1
SCHEMBL398009 0.78 CYP2A6 (0.44) CYP2A6KEAP1KDM4EMAPTMEN1
SCHEMBL30807019 0.77 DAO (0.55) CYP2A6KEAP1KDM4EMAPTMEN1
SCHEMBL890079 0.77 DAO (0.55) CYP2A6KEAP1KDM4EMAPTMEN1
SCHEMBL1709827 0.76 BRD4 (0.59) CYP2A6KEAP1KDM4EMAPTMEN1
SCHEMBL614723 0.74 LMNA (0.56) CYP2A6KEAP1HRH4ALDH1A1GAA
SCHEMBL2993745 0.74 KEAP1 (0.52) CYP2A6KEAP1KDM4EMEN1KMT2A
SCHEMBL20101387 0.74 KEAP1 (0.44) CYP2A6KEAP1KDM4EMAPTAXL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5752982-A DYEING HAIR IN LIGHTFAST, WASHFAST COLORS L'OREAL (FR) 1998-05-19 US claimed
EP-0424261-B1 Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent OREAL (FR) 1996-01-03 EP claimed
EP-0578735-B1 NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS OREAL (FR) 1996-01-03 EP claimed
EP-0497697-B1 Keratinous fibres dyeing process with isatine associated with an aminoindol or an aminoindoline, and composition therefor OREAL (FR) 1995-12-06 EP claimed
EP-0460996-B1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative OREAL (FR) 1994-09-14 EP claimed
EP-0425345-B1 Keratinic fibres dyeing process with amino-indoles, composition and use devices OREAL (FR) 1994-09-14 EP claimed
EP-0578735-A1 NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS. OREAL (FR) 1994-01-19 EP claimed
US-5254135-A Applying indole dye, developing with oxidizing system L'OREAL (FR) 1993-10-19 US claimed
US-5190564-A PROCESS FOR DYEING KERATINOUS FIBRES COMBINING ISATIN OR ITS DERIVATIVES WITH AN AMINOINDOLE OR AN AMINOINDOLINE, AND COMPOSITIONS USED L'OREAL (FR) 1993-03-02 US claimed
US-5180400-A METHOD FOR DYEING KERATINOUS FIBRES USING AN AMINOINDOLE IN COMBINATION WITH A QUINONE DERIVATIVE L'OREAL (FR) 1993-01-19 US claimed
WO-1992017157-A1 NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS L'OREAL (FR) 1992-10-15 WO claimed
EP-0497697-A1 Keratinous fibres dyeing process with isatine associated with an aminoindol or an aminoindoline, and composition therefor L'OREAL (FR) 1992-08-05 EP claimed
EP-0460996-A1 Keratinic fibres dyeing process with an aminoindol associated with a quinone derivative L'OREAL (FR) 1991-12-11 EP claimed
CN-1051669-A With the method for amino indole dyeing keratinous fibres, compositions and facilities and equipments OREAL (FR) 1991-05-29 CN claimed
CN-1051670-A Contain the dyeing composition for keratinous fibres of oxidation dye parent and amino indole colour former, the colouring method that uses these compositionss and noval chemical compound OREAL (FR) 1991-05-29 CN claimed
EP-0425345-A1 Keratinic fibres dyeing process with amino-indoles, composition and use devices L'OREAL (FR) 1991-05-02 EP claimed
EP-0424261-A1 Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent L'OREAL (FR) 1991-04-24 EP claimed
US-20250263760-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-08-21 US disclosed
EP-0425345-A1 Keratinic fibres dyeing process with amino-indoles, composition and use devices L'OREAL (FR) 1991-05-02 EP disclosed
EP-0424261-A1 Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent L'OREAL (FR) 1991-04-24 EP disclosed