SCHEMBL394632

SCHEMBL394632

NCC(CCCO)(CCCO)CCCO

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 2/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ARG2 P78540 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2582243 0.94 ALDH1A1 (0.33) ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10
SCHEMBL1352447 0.80 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL1012045 0.79 SMN1; SMN2 (0.41) ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10
SCHEMBL6472790 0.79 TSHR (0.39) ALDH1A1TSHRSMN1; SMN2LMNA
SCHEMBL1352707 0.79 ALDH1A1 (0.39) ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10
Water SCHEMBL28821923 0.78 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL15800756 0.75 ALDH1A1 (0.35) ALDH1A1TSHRARG2
SCHEMBL15694681 0.73 ALDH1A1 (0.37) ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10
SCHEMBL31040519 0.73 LMNA (0.42) ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10
SCHEMBL2639383 0.73 SMN1; SMN2 (0.37) ALDH1A1TSHRSMN1; SMN2LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8536228-B2 Transdermal compositions MICRODERMIS CORPORATION (US) 2013-09-17 US claimed
US-7893285-B2 Transdermal compositions MICRODERMIS CORPORATION (US) 2011-02-22 US claimed
US-7888393-B2 Transdermal compositions MICRODERMIS CORPORATION (US) 2011-02-15 US claimed
US-20100227929-A1 TRANSDERMAL COMPOSITIONS DRS. SOLUTIONS, LLC (US) 2010-09-09 US claimed
US-20100197795-A1 TRANSDERMAL COMPOSITIONS DRS. SOLUTIONS, LLC (US) 2010-08-05 US claimed
US-20090169610-A1 Liposome Preparation SIEMENS AKTIENGESELLSCHAFT (DE) 2009-07-02 US claimed
EP-1980243-A1 LIPOSOME PREPARATION Takeda Pharmaceutical Company Limited (JP) 2008-10-15 EP claimed
US-20070286896-A1 Therapeutic or Diagnostic Drug for Inflammatory Disease Comprising Targeting Liposome NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 2007-12-13 US claimed
US-20070160657-A1 Targeting and intestinal-absorption controlled liposome having sugar chain and therapeutic drug for cancer and diagnostic drug containing the liposome NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE (JP) 2007-07-12 US claimed
US-20060193906-A1 Sugar-modified liposome and products comprising the liposome NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 2006-08-31 US claimed
EP-1655038-A1 TARGET-DIRECTED AND ENTERIC ABSORPTION-CONTROLLED LIPOSOME HAVING SUGAR CHAIN AND CANCER REMEDY AND DIAGNOSTIC CONTAINING THE SAME National Institute of Advanced Industrial Science and Technology (JP) 2006-05-10 EP claimed
EP-1655022-A1 REMEDY OR DIAGNOSTIC FOR INFLAMMATORY DISEASE CONTAINING TARGET-DIRECTING LIPOSOME National Institute of Advanced Industrial Science and Technology (JP) 2006-05-10 EP claimed
US-9084821-B2 Transdermal compositions MICRODERMIS CORPORATION (US) 2015-07-21 US disclosed
US-20130251763-A1 TRANSDERMAL COMPOSITIONS MICRODERMIS CORPORATION (US) 2013-09-26 US disclosed
US-8536228-B2 Transdermal compositions MICRODERMIS CORPORATION (US) 2013-09-17 US disclosed
US-20130011466-A1 LIPOSOME ENCAPSULATING AMMINE-PLATINUM COMPLEX AT HIGH CONCENTRATION, AND METHOD FOR PRODUCTION OF THE LIPOSOME KATAYAMA CHEMICAL INDUSTRIES CO., LTD. (JP) 2013-01-10 US disclosed
EP-1655038-A1 TARGET-DIRECTED AND ENTERIC ABSORPTION-CONTROLLED LIPOSOME HAVING SUGAR CHAIN AND CANCER REMEDY AND DIAGNOSTIC CONTAINING THE SAME National Institute of Advanced Industrial Science and Technology (JP) 2006-05-10 EP disclosed
EP-1655022-A1 REMEDY OR DIAGNOSTIC FOR INFLAMMATORY DISEASE CONTAINING TARGET-DIRECTING LIPOSOME National Institute of Advanced Industrial Science and Technology (JP) 2006-05-10 EP disclosed
US-20040122105-A1 Transdermal compositions DRSS GLOBAL, LLC 2004-06-24 US disclosed
WO-2004026259-A2 TRANSDERMAL COMPOSITIONS BETTLE GRISCOM III (US) 2004-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130251763-A1 TRANSDERMAL COMPOSITIONS S100A10, TMSB10, FFAR3 ALDH1A1 2659/4885TSHR 3358/4885SMN1; SMN2 4798/4885
US-20130011466-A1 LIPOSOME ENCAPSULATING AMMINE-PLATINUM COMPLEX AT HIGH CONCENTRATION, AND METHOD FOR PRODUCTION OF THE LIPOSOME SLC7A1, MLEC, PHOSPHO1 ALDH1A1 3725/4885TSHR 3243/4885SMN1; SMN2 3051/4885
US-20100197795-A1 TRANSDERMAL COMPOSITIONS S100A10, TMSB10, DGKG ALDH1A1 2629/4885TSHR 3464/4885SMN1; SMN2 4812/4885
US-20100227929-A1 TRANSDERMAL COMPOSITIONS S100A10, TMSB10, FFAR3 ALDH1A1 2659/4885TSHR 3358/4885SMN1; SMN2 4798/4885
US-20040122105-A1 Transdermal compositions S100A10, DGKG, COX6C ALDH1A1 2002/4885TSHR 4174/4885SMN1; SMN2 4737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.