SCHEMBL3946342

SCHEMBL3946342

CCOc1ccccc1OCC=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.53
MAPT P10636 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
GLA P06280 1/20 0.53
ALDH1A1 P00352 4/20 0.50
CTSS P25774 3/20 0.48
CTSK P43235 3/20 0.48
CTSL P07711 2/20 0.48
HCRTR1 O43613 1/20 0.47
CYP2C19 P33261 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HTR1A P08908 1/20 0.45
ADRA1D P25100 1/20 0.45
ADRA1A P35348 1/20 0.45
ADRA1B P35368 1/20 0.45
GAA P10253 1/20 0.43
LMNA P02545 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Diethoxybenzene SCHEMBL28074336 0.87 L3MBTL1 (0.57) L3MBTL1MAPTNPSR1GLAALDH1A1
SCHEMBL514581 0.83 CA1 (0.54) L3MBTL1CTSSCTSKCTSLCYP1A2
1,2-Diethoxybenzene SCHEMBL578986 0.82 ALDH1A1 (0.68) L3MBTL1MAPTNPSR1GLAALDH1A1
1,2-Diethoxybenzene SCHEMBL29428929 0.82 ALDH1A1 (0.68) L3MBTL1MAPTNPSR1GLAALDH1A1
SCHEMBL2557802 0.82 L3MBTL1 (0.56) L3MBTL1MAPTNPSR1ALDH1A1CTSS
SCHEMBL5311090 0.80 L3MBTL1 (0.59) L3MBTL1MAPTNPSR1GLAALDH1A1
1-Allyloxy-2-Ethoxybenzene SCHEMBL11755537 0.79 HPGD (0.51) L3MBTL1MAPTNPSR1GLAALDH1A1
SCHEMBL10509104 0.79 LIG1 (0.53) L3MBTL1MAPTALDH1A1CTSSCTSK
SCHEMBL669777 0.79 NPSR1 (0.51) NPSR1GLAALDH1A1CTSSCTSK
SCHEMBL2096024 0.79 L3MBTL1 (0.53) L3MBTL1MAPTNPSR1GLAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1786764-B1 PROCESS FOR PREPARING TAMSULOSIN SCINOPHARM SINGAPORE PTE LTD (SG) 2017-03-15 EP disclosed
US-7619116-B2 Intermediates for the synthesis of (R)-tamsulosin and of its pharmaceutically acceptable salts and process for their preparation Products Chimiques Auxiliaires Et de Synthese (FR) 2009-11-17 US disclosed
US-7619116-B2 Intermediates for the synthesis of (R)-tamsulosin and of its pharmaceutically acceptable salts and process for their preparation Products Chimiques Auxiliaires Et de Synthese (FR) 2009-11-17 US disclosed
US-7619116-B2 Intermediates for the synthesis of (R)-tamsulosin and of its pharmaceutically acceptable salts and process for their preparation Products Chimiques Auxiliaires Et de Synthese (FR) 2009-11-17 US disclosed
EP-1539684-B1 BENZENESULPHONAMIDES AND PROCESS FOR THEIR PREPARATION RICHTER GEDEON NYRT (HU) 2009-04-15 EP disclosed
WO-2008157272-A2 DEUTERIUM-ENRICHED TAMSULOSIN PROTIA LLC (US) 2008-12-24 WO disclosed
US-20080312328-A1 DEUTERIUM-ENRICHED TAMSULOSIN PROTIA, LLC (US) 2008-12-18 US disclosed
EP-1697316-B1 NOVEL INTERMEDIATES FOR THE SYNTHESIS OF (R)-TAMSULOSIN AND OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR THEIR PREPARATION PROD CHIM AUXILIAIRES ET DE SY (FR) 2008-10-08 EP disclosed
EP-1697316-B1 NOVEL INTERMEDIATES FOR THE SYNTHESIS OF (R)-TAMSULOSIN AND OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR THEIR PREPARATION PROD CHIM AUXILIAIRES ET DE SY (FR) 2008-10-08 EP disclosed
US-7332621-B2 Process for preparing Tamsulosin SCINOPHARM TAIWAN KTD. (TW) 2008-02-19 US disclosed
EP-1539684-A1 BENZENESULPHONAMIDES AND PROCESS FOR THEIR PREPARATION RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 2005-06-15 EP disclosed
US-6894188-B1 Tamsulosin derivative RANBAXY LABORATORY LIMITED (IN) 2005-05-17 US disclosed
EP-1501793-A1 TAMSULOSIN DERIVATIVE RANBAXY LABORATORIES, LTD. (IN) 2005-02-02 EP disclosed
WO-2004022532-A1 BENZENESULPHONAMIDES AND PROCESS FOR THEIR PREPARATION Richter Gedeon Vegyészeti Gyár Rt. (HU) 2004-03-18 WO disclosed
WO-2004016582-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF TAMSULOSIN HYDROCHLORIDE NATCO PHARMA LIMITED (IN) 2004-02-26 WO disclosed
WO-2003093227-A1 TAMSULOSIN DERIVATIVE RANBAXY LABORATORIES LIMITED (IN) 2003-11-13 WO disclosed
EP-0169581-B1 ANTITUSSIVE AND MUCUS REGULATING 2-SUBSTITUTED THIAZOLIDINES BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) 1989-12-06 EP disclosed
US-4857643-A Antitussive and mucus regulating 2-substituted thiazolidines BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1989-08-15 US disclosed
US-4798898-A BRONCHODILATORS BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1989-01-17 US disclosed
EP-0169581-A2 Antitussive and mucus regulating 2-substituted thiazolidines BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) 1986-01-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312328-A1 DEUTERIUM-ENRICHED TAMSULOSIN AVPR2, AVPR1B, AVPR1A L3MBTL1 4675/4885MAPT 3061/4885NPSR1 31/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.