Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4845588 | 0.95 | DPP4 (0.44) | TSHRDPP4RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4615013 | 0.95 | DPP4 (0.44) | TSHRDPP4RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL23854197 | 0.87 | TSHR (0.45) | TSHRDPP4RAB9ASMN1; SMN2POLB | |
| SCHEMBL70309 | 0.84 | FKBP1A (0.57) | FKBP1ATSHRRAB9ASMN1; SMN2POLB | |
| SCHEMBL9176935 | 0.84 | RAB9A (0.55) | RAB9AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL21225069 | 0.84 | RAB9A (0.55) | RAB9AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL1478184 | 0.81 | HSD17B10 (0.55) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL82116 | 0.81 | HSD17B10 (0.55) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1478166 | 0.81 | HSD17B10 (0.55) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL17327535 | 0.79 | CHRM2 (0.42) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204415-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |
| EP-3436444-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2019-02-06 | — | — | EP | disclosed |
| WO-2017171100-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-10-05 | — | — | WO | disclosed |
| WO-2009154300-A2 | HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-23 | — | — | WO | disclosed |
| WO-2008011130-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |