SCHEMBL70309

SCHEMBL70309

COC(=O)C1CCCCN1C(=O)OC

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 8/20 0.57
POLB P06746 1/20 0.53
PEPD P12955 2/20 0.44
XPNPEP1 Q9NQW7 1/20 0.44
TSHR P16473 1/20 0.42
LMNA P02545 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PKM P14618 1/20 0.42
KMT2A Q03164 1/20 0.42
ALOX5 P09917 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9546469 0.94 POLB (0.58) FKBP1APOLBPEPDXPNPEP1TSHR
SCHEMBL30599979 0.94 POLB (0.58) FKBP1APOLBPEPDXPNPEP1TSHR
SCHEMBL12566180 0.85 FKBP1A (0.57) FKBP1APOLBPEPDXPNPEP1LMNA
SCHEMBL17822411 0.85 FKBP1A (0.57) FKBP1APOLBPEPDXPNPEP1LMNA
SCHEMBL7451535 0.85 FKBP1A (0.57) FKBP1APOLBPEPDXPNPEP1LMNA
SCHEMBL14426630 0.85 FKBP1A (0.57) FKBP1APOLBPEPDXPNPEP1LMNA
SCHEMBL5965365 0.85 FKBP1A (0.57) FKBP1APOLBPEPDXPNPEP1LMNA
SCHEMBL3061683 0.85 FKBP1A (0.57) FKBP1APOLBPEPDXPNPEP1LMNA
SCHEMBL21225069 0.85 RAB9A (0.55) PEPDLMNARAB9ASMN1; SMN2
SCHEMBL9176935 0.85 RAB9A (0.55) PEPDLMNARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110317201-B Asymmetric synthesis method of (S, S) -2, 8-diazabicyclo [4,3,0] nonane 武汉理工大学 2022-03-01 CN disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 FKBP1A 3134/4885POLB 3973/4885PEPD 4048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.