Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799691 | 0.89 | CNR1 (0.35) | TSHRSMPD3 | |
| SCHEMBL5416781 | 0.81 | KDM4E (0.35) | SIGMAR1TSHR | |
| SCHEMBL5422207 | 0.80 | NOS3 (0.34) | SIGMAR1TSHR | |
| Hydrochloric Acid SCHEMBL6757419 | 0.79 | TSHR (0.33) | SIGMAR1TSHR | |
| SCHEMBL5422084 | 0.79 | ALDH1A1 (0.37) | SIGMAR1TSHR | |
| SCHEMBL14445294 | 0.79 | ALDH1A1 (0.37) | SIGMAR1TSHR | |
| SCHEMBL5424913 | 0.78 | CHRNB2 (0.37) | TSHR | |
| SCHEMBL5159269 | 0.78 | POLB (0.40) | TSHR | |
| SCHEMBL3944376 | 0.77 | TSHR (0.32) | SIGMAR1TSHR | |
| SCHEMBL5422957 | 0.76 | KDM2B (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1413286-B1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | OREAL (FR) | 2009-04-22 | — | — | EP | claimed |
| EP-1413286-A1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | L'OREAL (FR) | 2004-04-28 | — | — | EP | claimed |
| EP-1413286-B1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | OREAL (FR) | 2009-04-22 | — | — | EP | disclosed |
| EP-1413286-A1 | Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent | L'OREAL (FR) | 2004-04-28 | — | — | EP | disclosed |