Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 4/20 | 0.32 |
| ▸ | MMP9 | P14780 | 4/20 | 0.32 |
| ▸ | MMP13 | P45452 | 4/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952750 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MMP9MEN1KMT2A | |
| SCHEMBL146262 | 0.75 | — | — | |
| SCHEMBL3955174 | 0.73 | HCRTR1 (0.35) | ALDH1A1MEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL2079080 | 0.73 | MMP2 (0.30) | — | |
| SCHEMBL4297050 | 0.72 | HRH3 (0.34) | ALDH1A1CHRM3MEN1KMT2A | |
| SCHEMBL3547375 | 0.72 | — | — | |
| SCHEMBL2819757 | 0.72 | — | — | |
| SCHEMBL3950848 | 0.72 | CTSL (0.43) | ALDH1A1MEN1KMT2A | |
| SCHEMBL376577 | 0.72 | — | — | |
| SCHEMBL4298789 | 0.71 | HCRTR1 (0.36) | ALDH1A1KMT2AHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |