Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944379 | 0.93 | MMP1 (0.41) | MEN1KMT2AMMP1MMP2MMP9 | |
| SCHEMBL3946809 | 0.93 | MEN1 (0.45) | PKMMEN1KMT2A | |
| SCHEMBL3943534 | 0.92 | RXFP1 (0.40) | PKMRXFP1MEN1KMT2A | |
| SCHEMBL3950554 | 0.91 | PKM (0.52) | PKMRXFP1 | |
| SCHEMBL3950746 | 0.90 | RXFP1 (0.49) | PKMRXFP1MEN1KMT2ALMNA | |
| SCHEMBL3944160 | 0.88 | PKM (0.54) | PKMRXFP1 | |
| SCHEMBL3943104 | 0.87 | RXFP1 (0.44) | RXFP1MEN1KMT2A | |
| SCHEMBL13942747 | 0.87 | PKM (0.51) | PKMRXFP1MEN1KMT2AMMP1 | |
| SCHEMBL3942926 | 0.87 | HTT (0.51) | PKMMEN1KMT2ALMNA | |
| SCHEMBL13942745 | 0.87 | PKM (0.51) | PKMRXFP1MEN1KMT2AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |