Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944379 | 0.95 | MMP1 (0.41) | MEN1KMT2A | |
| SCHEMBL3947294 | 0.93 | PKM (0.46) | MEN1KMT2APKM | |
| SCHEMBL3943534 | 0.90 | RXFP1 (0.40) | MEN1KMT2APKM | |
| SCHEMBL3943104 | 0.88 | RXFP1 (0.44) | MEN1KMT2ATSHR | |
| SCHEMBL13942602 | 0.88 | MEN1 (0.47) | MEN1KMT2AGAATSHRBLM | |
| SCHEMBL3947411 | 0.87 | MEN1 (0.50) | MEN1KMT2APKM | |
| SCHEMBL3945382 | 0.86 | TP53 (0.46) | PKM | |
| SCHEMBL13942731 | 0.86 | PKM (0.49) | MEN1KMT2APKM | |
| SCHEMBL13942057 | 0.86 | MMP1 (0.41) | MEN1KMT2A | |
| SCHEMBL13942600 | 0.86 | MEN1 (0.54) | MEN1KMT2AGAATSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2009020457-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |