Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 7/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5130509 | 0.90 | KCNN4 (0.52) | MAPTKMT2ACES1KCNN4CYP1A2 | |
| SCHEMBL10878702 | 0.82 | MAPT (0.47) | MAPTKMT2ACES1KCNN4CYP1A2 | |
| SCHEMBL5257950 | 0.79 | KCNN4 (0.47) | MAPTKMT2ACES1KCNN4CYP1A2 | |
| SCHEMBL30010927 | 0.79 | CES1 (0.43) | MAPTKMT2ACES1KCNN4CYP1A2 | |
| SCHEMBL3905516 | 0.78 | MAPT (0.55) | MAPTKMT2ACES1KCNN4CYP1A2 | |
| SCHEMBL1454439 | 0.78 | CES1 (0.63) | MAPTKMT2ACES1KCNN4CYP1A2 | |
| SCHEMBL10878706 | 0.77 | MAPT (0.50) | MAPTKMT2ACES1KCNN4CYP1A2 | |
| SCHEMBL4554194 | 0.76 | MAPT (0.59) | MAPTKMT2ACES1KCNN4CYP1A2 | |
| SCHEMBL5560839 | 0.74 | MAPT (0.47) | MAPTKMT2ACES1KCNN4CYP1A2 | |
| SCHEMBL617934 | 0.73 | MAPT (0.55) | MAPTKMT2ACES1KCNN4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514425-B2 | Short-acting sedative hypnotic agents for anesthesia and sedation | THERAVANCE, INC. (US) | 2009-04-07 | — | — | US | claimed |
| US-20060116424-A1 | Short-acting sedative hypnotic agents for anesthesia and sedation | THERAVANCE BIOPHARMA R&D IP, LLC | 2006-06-01 | — | — | US | claimed |
| EP-0335046-B1 | Method for producing 2,4-dihydroxyquinoline derivatives | MITSUBISHI CHEM IND (JP) | 1993-12-01 | — | — | EP | disclosed |
| US-4904787-A | CYCLIZATION USING POLYPHOSPHORIC ACID; NONHYDROLIZING, ONE STEP | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0335046-A1 | Method for producing 2,4-dihydroxyquinoline derivatives | MITSUBISHI KASEI CORPORATION (JP) | 1989-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116424-A1 | Short-acting sedative hypnotic agents for anesthesia and sedation | GABRA5, GABRA6, GABRA2 | MAPT 2821/4885KMT2A 378/4885CES1 1614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.