Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | SCN4A | P35499 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722815 | 0.81 | EPHX2 (0.77) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL9722817 | 0.81 | RAB9A (0.65) | NPC1RAB9ASMN1; SMN2LMNAUSP2 | |
| SCHEMBL9722750 | 0.81 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL15271195 | 0.80 | SCD (0.74) | NPC1RAB9ASMN1; SMN2LMNAGMNN | |
| SCHEMBL5786138 | 0.79 | TRPV1 (0.71) | NPC1RAB9ASMN1; SMN2LMNAMAPK1 | |
| Riluzole SCHEMBL29359189 | 0.78 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2LMNAGMNN | |
| Riluzole SCHEMBL78905 | 0.78 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2LMNAGMNN | |
| Riluzole SCHEMBL8913448 | 0.78 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2LMNAGMNN | |
| Riluzole SCHEMBL5053829 | 0.78 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2LMNAGMNN | |
| Riluzole SCHEMBL4443848 | 0.77 | RAB9A (0.82) | NPC1RAB9ASMN1; SMN2LMNAGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514460-B2 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2009-04-07 | — | — | US | disclosed |
| EP-1674467-A1 | 2,5- and 2,6-disubstituted benzazole derivatives useful as protein kinase inhibitors | 4SC AG (DE) | 2006-06-28 | — | — | EP | disclosed |
| US-20060135782-A1 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135782-A1 | Benzazole analogues and uses thereof | DCK, SBK3, DAPK3 | NPC1 4134/4885RAB9A 2582/4885SMN1; SMN2 4580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.