Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394780 | 0.86 | TRPA1 (0.46) | ESR1TRPA1ATMTDP1TP53 | |
| SCHEMBL30628003 | 0.86 | TRPA1 (0.46) | ESR1TRPA1ATMTDP1TP53 | |
| SCHEMBL980178 | 0.84 | ESR1 (0.49) | ESR1TRPA1ATMTDP1ESR2 | |
| SCHEMBL8827949 | 0.82 | ALDH1A1 (0.48) | ESR1TRPA1ATMTDP1TP53 | |
| SCHEMBL18955088 | 0.79 | TRPA1 (0.36) | ESR1TRPA1ATMTSHRCYP1A2 | |
| SCHEMBL29359879 | 0.73 | ESR1 (0.43) | ESR1TRPA1ATMTDP1TP53 | |
| SCHEMBL36472 | 0.73 | ESR1 (0.43) | ESR1TRPA1ATMTDP1TP53 | |
| SCHEMBL31612514 | 0.71 | GABRA1 (0.45) | ESR1TRPA1ATMTDP1TP53 | |
| SCHEMBL2051069 | 0.71 | TRPA1 (0.46) | ESR1TRPA1ATMTDP1TP53 | |
| SCHEMBL4503429 | 0.71 | GABRA1 (0.45) | ESR1TRPA1ATMTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269367-A1 | Prepolymer containing a Liquid Hardness Agent For Open Cell Foams | NEILL PAUL L | 2008-10-30 | — | — | US | disclosed |
| EP-1622960-A4 | LIQUID HARDNESS AGENT FOR OPEN CELL FOAMS | STEPAN CO (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007047661-A2 | PREPOLYMER CONTAINING A LIQUID HARDNESS AGENT FOR OPEN CELL FOAMS | STEPAN COMPANY (US) | 2007-04-26 | — | — | WO | disclosed |
| US-20060169948-A1 | Liquid hardness agent for open cell foams | NEILL PAUL L | 2006-08-03 | — | — | US | disclosed |
| EP-1622960-A2 | LIQUID HARDNESS AGENT FOR OPEN CELL FOAMS | STEPAN COMPANY (US) | 2006-02-08 | — | — | EP | disclosed |
| US-20040259967-A1 | Liquid hardness agent for open cell foams | STEPAN COMPANY | 2004-12-23 | — | — | US | disclosed |
| WO-2004094506-A2 | LIQUID HARDNESS AGENT FOR OPEN CELL FOAMS | STEPAN COMPANY (US) | 2004-11-04 | — | — | WO | disclosed |