Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456971 | 0.73 | MKNK1 (0.37) | RIPK3AKT1AKT2PDE4AMKNK1 | |
| SCHEMBL3954508 | 0.65 | DYRK1A (0.32) | — | |
| SCHEMBL3948108 | 0.64 | ALOX5 (0.36) | RIPK3AKT1AKT2PDE4A | |
| SCHEMBL1745964 | 0.63 | PDE4A (0.48) | AKT1AKT2PDE4AMKNK1 | |
| SCHEMBL22189751 | 0.60 | AKT1 (0.48) | RIPK3AKT1AKT2PDE4A | |
| SCHEMBL17492375 | 0.60 | PDE4B (0.62) | PDE4A | |
| SCHEMBL1746576 | 0.59 | MKNK1 (0.49) | RIPK3AKT1AKT2PDE4AMKNK1 | |
| SCHEMBL10437261 | 0.59 | PDE10A (0.41) | PDE4AMKNK1 | |
| SCHEMBL477032 | 0.59 | MKNK1 (0.53) | PDE4AMKNK1 | |
| SCHEMBL14034448 | 0.59 | PDE4A (0.43) | PDE4AMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009029625-A1 | 4- [HETEROCYCLYL-METHYL] -8-FLUORO-QUINOLIN-2-ONES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | KALYPSYS, INC. (US) | 2009-03-05 | — | — | WO | disclosed |