Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.51 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.38 |
| ▸ | LIPC | P11150 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948188 | 1.00 | EPHX2 (0.51) | EPHX2TEAD1ADRB2PARP10LIPE | |
| SCHEMBL3937008 | 0.95 | PARP10 (0.49) | EPHX2TEAD1ADRB2PARP10LIPE | |
| SCHEMBL3937004 | 0.95 | PARP10 (0.49) | EPHX2TEAD1ADRB2PARP10LIPE | |
| SCHEMBL3946996 | 0.92 | EPHX2 (0.44) | EPHX2TEAD1ADRB2PARP10LIPE | |
| SCHEMBL3946995 | 0.92 | EPHX2 (0.44) | EPHX2TEAD1ADRB2PARP10LIPE | |
| SCHEMBL3946999 | 0.92 | EPHX2 (0.44) | EPHX2TEAD1ADRB2PARP10LIPE | |
| SCHEMBL4025146 | 0.90 | LMNA (0.51) | EPHX2TEAD1ADRB2NR4A1NR4A2 | |
| SCHEMBL4025148 | 0.90 | LMNA (0.51) | EPHX2TEAD1ADRB2NR4A1NR4A2 | |
| SCHEMBL4205841 | 0.90 | EPHX2 (0.41) | EPHX2TEAD1ADRB2PARP10NR4A1 | |
| SCHEMBL4025153 | 0.90 | LMNA (0.51) | EPHX2TEAD1ADRB2NR4A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-2050734-A1 | PENTADIENAMIDE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | PRMT1, REN, NGLY1 | EPHX2 3390/4885TEAD1 4389/4885ADRB2 1963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.