Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025153 | 1.00 | LMNA (0.51) | LMNAALDH1A1SENP8SENP6CASP3 | |
| SCHEMBL4025146 | 1.00 | LMNA (0.51) | LMNAALDH1A1SENP8SENP6CASP3 | |
| SCHEMBL3948188 | 0.90 | EPHX2 (0.51) | EPHX2TEAD1CYP1A1CYP1B1ADRB2 | |
| SCHEMBL3948185 | 0.90 | EPHX2 (0.51) | EPHX2TEAD1CYP1A1CYP1B1ADRB2 | |
| SCHEMBL3937008 | 0.87 | PARP10 (0.49) | LMNAALDH1A1NPC1RAB9AEPHX2 | |
| SCHEMBL3937004 | 0.87 | PARP10 (0.49) | LMNAALDH1A1NPC1RAB9AEPHX2 | |
| SCHEMBL4205850 | 0.86 | EPHX2 (0.41) | LMNAALDH1A1SENP8SENP6CASP3 | |
| SCHEMBL4205845 | 0.86 | EPHX2 (0.41) | LMNAALDH1A1SENP8SENP6CASP3 | |
| SCHEMBL4205841 | 0.86 | EPHX2 (0.41) | LMNAALDH1A1SENP8SENP6CASP3 | |
| SCHEMBL3946996 | 0.84 | EPHX2 (0.44) | EPHX2TEAD1CYP1A1CYP1B1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-2050734-A1 | PENTADIENAMIDE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | PRMT1, REN, NGLY1 | LMNA 3654/4885ALDH1A1 1143/4885SENP8 2282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.