Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 8/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862914 | 1.00 | ABCB1 (0.41) | ABCB1SRCPRMT5UCHL1PARP1 | |
| SCHEMBL3955172 | 0.91 | HDAC8 (0.38) | ABCB1 | |
| SCHEMBL4297046 | 0.90 | ABCB1 (0.39) | ABCB1SRCPRMT5 | |
| SCHEMBL4299042 | 0.89 | ABHD6 (0.36) | — | |
| SCHEMBL2202034 | 0.86 | GPR119 (0.39) | ABCB1SRC | |
| SCHEMBL4602385 | 0.86 | GPR119 (0.39) | ABCB1SRC | |
| SCHEMBL30101468 | 0.86 | CYSLTR1 (0.38) | ABCB1 | |
| SCHEMBL12037518 | 0.86 | USP30 (0.45) | ABCB1SRC | |
| SCHEMBL12021060 | 0.86 | USP30 (0.45) | ABCB1SRC | |
| SCHEMBL4292542 | 0.86 | ABCB1 (0.47) | ABCB1SRCPRMT5UCHL1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |