Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 6/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 4/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202034 | 1.00 | GPR119 (0.39) | GPR119TSHRABCB1SSTR4SSTR1 | |
| SCHEMBL7862914 | 0.86 | ABCB1 (0.41) | ABCB1SRC | |
| SCHEMBL3948290 | 0.86 | ABCB1 (0.41) | ABCB1SRC | |
| SCHEMBL2200981 | 0.83 | ABCB1 (0.39) | GPR119ABCB1SSTR4SSTR1SRC | |
| SCHEMBL2201807 | 0.83 | POLB (0.42) | GPR119TSHRSSTR4SSTR1SRC | |
| SCHEMBL4603500 | 0.83 | POLB (0.42) | GPR119TSHRSSTR4SSTR1SRC | |
| SCHEMBL2547741 | 0.82 | ITGA4 (0.41) | GPR119SSTR4SSTR1GRM2 | |
| SCHEMBL1241283 | 0.81 | GPR119 (0.39) | GPR119ABCB1SRCMEN1KMT2A | |
| SCHEMBL3955172 | 0.81 | HDAC8 (0.38) | GPR119ABCB1ALDH1A1 | |
| SCHEMBL4292542 | 0.80 | ABCB1 (0.47) | GPR119ABCB1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912994-B1 | ADENINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2014-03-12 | — | — | EP | disclosed |
| EP-1912994-A1 | ADENINE DERIVATIVES | Merck Patent GmbH (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017069-A1 | ADENINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | WO | disclosed |