Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950223 | 0.84 | FFAR4 (0.34) | CHRM3FFAR4NPC1POLBCASP3 | |
| SCHEMBL3954707 | 0.82 | TDP1 (0.32) | CHRM3FFAR4 | |
| SCHEMBL3950891 | 0.82 | — | — | |
| SCHEMBL3952247 | 0.81 | FFAR4 (0.33) | CHRM3FFAR4NPC1POLBCASP3 | |
| SCHEMBL3949073 | 0.80 | — | — | |
| SCHEMBL3955604 | 0.78 | ALDH1A1 (0.34) | POLBHPGDMAPT | |
| SCHEMBL3950301 | 0.73 | CPT2 (0.41) | POLB | |
| SCHEMBL3952310 | 0.72 | — | — | |
| SCHEMBL3946190 | 0.70 | SSTR4 (0.34) | FFAR4MAPT | |
| SCHEMBL3949539 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |