Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | HTR7 | P34969 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950238 | 0.85 | MAPK1 (0.37) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3949447 | 0.83 | CTSL (0.41) | CPT2CPT1ACPT1BHTR1AHTR7 | |
| SCHEMBL3947518 | 0.81 | MMP2 (0.36) | CPT2CPT1ACPT1BALDH1A1 | |
| SCHEMBL3954107 | 0.80 | MCL1 (0.38) | MEN1KMT2AALDH1A1MCL1 | |
| SCHEMBL3948717 | 0.78 | CPT1A (0.46) | CPT2CPT1ACPT1BGAAKMT2A | |
| SCHEMBL3951883 | 0.76 | L3MBTL1 (0.44) | CPT2CPT1ACPT1BMEN1KMT2A | |
| SCHEMBL3950223 | 0.74 | FFAR4 (0.34) | MEN1KMT2ALMNAPOLB | |
| SCHEMBL3952247 | 0.73 | FFAR4 (0.33) | MEN1KMT2APOLB | |
| SCHEMBL3955811 | 0.73 | CPT2 (0.47) | CPT2CPT1ACPT1BARHTR1A | |
| SCHEMBL3948516 | 0.73 | SCN3A (0.34) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |