Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946190 | 0.88 | SSTR4 (0.34) | FFAR4SSTR4MEN1KMT2A | |
| SCHEMBL3950223 | 0.87 | FFAR4 (0.34) | FFAR4CHRM3NPC1POLBCASP3 | |
| SCHEMBL3948516 | 0.81 | SCN3A (0.34) | FFAR4CHRM3NPC1POLBCASP3 | |
| SCHEMBL3954707 | 0.80 | TDP1 (0.32) | FFAR4CHRM3TDP1MEN1KMT2A | |
| SCHEMBL3952784 | 0.79 | — | — | |
| SCHEMBL3949505 | 0.74 | ALDH1A1 (0.35) | NPC1RAB9ATDP1MEN1KMT2A | |
| SCHEMBL3950301 | 0.73 | CPT2 (0.41) | POLBMEN1KMT2A | |
| SCHEMBL8061878 | 0.62 | SRC (0.43) | — | |
| Trifluoroacetic Acid SCHEMBL2648351 | 0.60 | PARP15 (0.50) | — | |
| Trifluoroacetic Acid SCHEMBL2648352 | 0.60 | PARP15 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026197-A1 | NOVEL CATHEPSIN C INHIBITORS AND THEIR USE | GLAXO GROUP LIMITED (GB) | 2009-02-26 | — | — | WO | disclosed |