Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.52 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15800695 | 0.80 | GRIN1 (0.48) | SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2 | |
| SCHEMBL6335562 | 0.78 | HIF1A (0.56) | SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2 | |
| SCHEMBL721250 | 0.78 | HIF1A (0.56) | SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2 | |
| SCHEMBL9421220 | 0.76 | MAOA (0.56) | SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2 | |
| SCHEMBL1630522 | 0.74 | MIF (0.58) | SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2 | |
| SCHEMBL7484724 | 0.74 | HIF1A (0.52) | SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2 | |
| SCHEMBL921157 | 0.74 | HIF1A (0.52) | SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2 | |
| SCHEMBL5370459 | 0.74 | TDP1 (0.52) | SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2 | |
| SCHEMBL944031 | 0.74 | HIF1A (0.52) | SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2 | |
| SCHEMBL15999404 | 0.74 | HIF1A (0.52) | SMN1; SMN2CYP2A6HTR2ATAAR1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318738-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2012-11-27 | — | — | US | disclosed |
| US-7576084-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2009-08-18 | — | — | US | disclosed |
| US-7566711-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2009-07-28 | — | — | US | disclosed |
| US-7232822-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2007-06-19 | — | — | US | disclosed |
| US-4639441-A | ANTIBACTERIAL PENICILLINS | SANKYO COMPANY LIMITED (JP) | 1987-01-27 | — | — | US | disclosed |