Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.56 |
| ▸ | MIF | P14174 | 3/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.56 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.56 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897206 | 0.90 | HTR3A (0.57) | HIF1AMIFCYP2A6TRPA1CYP2E1 | |
| SCHEMBL4699868 | 0.88 | HTR2A (0.58) | HIF1AMIFCYP2A6TRPA1CYP2E1 | |
| SCHEMBL9819891 | 0.88 | NAAA (0.60) | MIFNAAAHTR3AMAPTSIGMAR1 | |
| SCHEMBL9819728 | 0.88 | NAAA (0.60) | MIFNAAAHTR3AMAPTSIGMAR1 | |
| SCHEMBL6560088 | 0.88 | MIF (0.47) | HIF1AMIFCYP2A6TRPA1CYP2E1 | |
| SCHEMBL9819903 | 0.88 | NAAA (0.60) | MIFNAAAHTR3AMAPTSIGMAR1 | |
| SCHEMBL2643014 | 0.87 | MIF (0.50) | HIF1AMIFCYP2A6TRPA1CYP2E1 | |
| SCHEMBL1885696 | 0.85 | MIF (0.54) | HIF1AMIFCYP2A6TRPA1CYP2E1 | |
| SCHEMBL10431399 | 0.85 | TDP1 (0.54) | HIF1AMIFCYP2A6TRPA1CYP2E1 | |
| SCHEMBL9035864 | 0.84 | KCNH2 (0.49) | HIF1AMIFCYP2A6TRPA1CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090043111-A1 | Novel process for ropinirole preparation | LIU MEIZHENG | 2009-02-12 | — | — | US | claimed |
| EP-0873118-A1 | TRANSDERMAL ADMINISTRATION OF ROPINIROLE AND ANALOGS THEREOF | SMITHKLINE BEECHAM PLC (GB) | 1998-10-28 | — | — | EP | claimed |
| US-5807570-A | DOPAMINE AGONIST | CYGNUS, INC. (US) | 1998-09-15 | — | — | US | claimed |
| WO-1997011696-A1 | TRANSDERMAL ADMINISTRATION OF ROPINIROLE AND ANALOGS THEREOF | CYGNUS, INC. (US) | 1997-04-03 | — | — | WO | claimed |
| US-4452808-A | HYPOTENSIVE AGENTS | SMITHKLINE BECKMAN CORPORATION (US) | 1984-06-05 | — | — | US | claimed |
| US-4406875-A | Radiolabeled amine compounds and their use | BYK-MALLINCKRODT CIL B.V. (NL) | 1983-09-27 | — | — | US | claimed |
| WO-1980001685-A1 | RADIOLABELED AMINE COMPOUNDS AND THEIR USE | BYK MALLINCKRODT CIL BV (NL) | 1980-08-21 | — | — | WO | claimed |
| US-4016263-A | BACTERICIDES | BOEHRINGER INGELHEIM GMBH (DT) | 1977-04-05 | — | — | US | claimed |
| US-11980092-B2 | Organic electroluminescence element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2024-05-07 | — | — | US | disclosed |
| US-11925114-B2 | Indenocarbazole compound and organic electroluminescence device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2024-03-05 | — | — | US | disclosed |
| WO-2024005030-A1 | DIPHENYLETHENE-BASED COMPOUND, LIGHT ABSORBER, RESIN COMPOSITION, AND USE THEREOF | 山本化成株式会社 | 2024-01-04 | — | — | WO | disclosed |
| EP-3432688-B1 | ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO LTD (JP) | 2023-12-20 | — | — | EP | disclosed |
| EP-3275969-B1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, LIGHT-EMITTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO LTD (JP) | 2023-10-04 | — | — | EP | disclosed |
| US-11718758-B2 | Aqueous dispersion of colored particles | MITSUBISHI PENCIL COMPANY, LIMITED (JP) | 2023-08-08 | — | — | US | disclosed |
| US-4091210-A | Preparation of 3-alkyl-3-cephem-4-carboxylic acid compounds from dithio isopropenyl azetidine carboxylic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-05-23 | — | — | US | disclosed |
| US-4084049-A | CEPHALOSPORIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1978-04-11 | — | — | US | disclosed |
| US-4028112-A | MEROCYANINE DYE WITH OXAZOLE NUCLEUS | FUJI PHOTO FILM CO., LTD. (JA) | 1977-06-07 | — | — | US | disclosed |
| US-4016263-A | BACTERICIDES | BOEHRINGER INGELHEIM GMBH (DT) | 1977-04-05 | — | — | US | disclosed |
| US-3962527-A | Novel polymers and photographic elements containing same | EASTMAN KODAK COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3954732-A | BACTERICIDAL PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043111-A1 | Novel process for ropinirole preparation | PAH, DRD4, DBH | HIF1A 1421/4885MIF 2966/4885CYP2A6 918/4885 |
| US-11925114-B2 | Indenocarbazole compound and organic electroluminescence device | OXA1L, KCNJ1, ABCB1 | HIF1A 3570/4885MIF 1377/4885CYP2A6 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.