SCHEMBL10877367

SCHEMBL10877367

CCCC(Oc1ccccc1Cl)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 11/20 0.56
PPARG P37231 10/20 0.56
ALDH1A1 P00352 3/20 0.49
SLC6A9 P48067 1/20 0.44
KMT2A Q03164 3/20 0.43
HPGD P15428 2/20 0.43
LMNA P02545 1/20 0.43
MEN1 O00255 2/20 0.43
MAPT P10636 1/20 0.43
CXCL8 P10145 1/20 0.42
POLB P06746 1/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9322236 0.88 CTRC (0.49) PPARAPPARGALDH1A1SLC6A9
SCHEMBL8935901 0.87 PPARA (0.51) PPARAPPARGALDH1A1SLC6A9KMT2A
SCHEMBL5063037 0.87 PPARA (0.51) PPARAPPARGALDH1A1SLC6A9KMT2A
SCHEMBL10875112 0.82 PPARA (0.64) PPARAPPARGALDH1A1HPGDMAPT
SCHEMBL7507747 0.81 PPARG (0.66) PPARAPPARGALDH1A1HPGDLMNA
SCHEMBL8082709 0.81 PPARG (0.56) PPARAPPARGKMT2ALMNAMEN1
SCHEMBL2571460 0.81 PPARG (0.56) PPARAPPARGALDH1A1KMT2AHPGD
SCHEMBL11547048 0.81 ALDH1A1 (0.42) PPARAPPARGALDH1A1SLC6A9KMT2A
SCHEMBL1814149 0.81 PPARA (0.51) PPARAPPARGALDH1A1KMT2AHPGD
Hydrochloric Acid SCHEMBL8074440 0.80 PPARG (0.55) PPARAPPARGKMT2ALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0202566-A2 Phenoxy alkyl triazoles NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-11-26 EP disclosed