Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.56 |
| ▸ | PPARA | Q07869 | 11/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8074440 | 0.98 | PPARG (0.55) | PPARGPPARAPTGESALOX5LMNA | |
| SCHEMBL8081953 | 0.88 | PPARA (0.42) | PPARGPPARALMNATSHRKMT2A | |
| SCHEMBL8935797 | 0.87 | PPARA (0.49) | PPARGPPARALMNATSHRKMT2A | |
| SCHEMBL1245341 | 0.87 | PPARA (0.49) | PPARGPPARALMNATSHRKMT2A | |
| SCHEMBL8074435 | 0.86 | PPARA (0.41) | PPARGPPARALMNATSHRKMT2A | |
| SCHEMBL8086173 | 0.86 | PPARA (0.41) | PPARGPPARALMNATSHRKMT2A | |
| Hydrochloric Acid SCHEMBL8074407 | 0.86 | PPARA (0.48) | PPARGPPARALMNATSHRKMT2A | |
| SCHEMBL8074376 | 0.85 | POLB (0.43) | PPARGPPARALMNATSHRKMT2A | |
| SCHEMBL5533566 | 0.82 | PKM (0.51) | PPARGPPARALMNARAB9A | |
| SCHEMBL21057214 | 0.82 | PPARA (0.50) | PPARGPPARAPTGESALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063810-A | ENANTIOMORPHS | SYNTHELABO (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0888324-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997032870-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-09-12 | — | — | WO | disclosed |