Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 6/20 | 0.61 |
| ▸ | ADH1C | P00326 | 4/20 | 0.61 |
| ▸ | ADH4 | P08319 | 1/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2874295 | 0.84 | — | — | |
| SCHEMBL6006488 | 0.78 | ADH1A (0.94) | ADH1AADH1CADH4 | |
| SCHEMBL6005197 | 0.76 | ADH1A (1.00) | ADH1AADH1CADH4 | |
| SCHEMBL4496323 | 0.75 | ADH1A (1.00) | ADH1AADH1CADH4 | |
| SCHEMBL5122418 | 0.74 | ADH1A (1.00) | ADH1AADH1CADH4 | |
| SCHEMBL27510273 | 0.73 | PIK3CD (0.36) | ADH1AADH1CADH4PIK3CD | |
| SCHEMBL28057896 | 0.73 | ADH1A (0.33) | ADH1AADH1CADH4PIK3CD | |
| SCHEMBL772050 | 0.73 | ADH1A (0.60) | ADH1AADH1CADH4PIK3CD | |
| SCHEMBL3160136 | 0.73 | ADH1A (1.00) | ADH1AADH1CADH4 | |
| Cyclobutyl(Cyclopentyl)Formamide SCHEMBL4315833 | 0.73 | ADH1A (1.00) | ADH1AADH1CADH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048269-A1 | CHEMICAL COMPOUNDS-821 | ASTRAZENECA AB (SE) | 2009-02-19 | — | — | US | disclosed |
| WO-2009022171-A1 | PYRIDINYIIOXY PYRIDINES AS ALK5 INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048269-A1 | CHEMICAL COMPOUNDS-821 | TGFBR1, TGFBR2, SMAD3 | ADH1A 1808/4885ADH1C 2050/4885ADH4 4208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.