SCHEMBL28057896

SCHEMBL28057896

NN(C=O)C1CCOCC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 5/20 0.33
ADH1C P00326 3/20 0.33
PIK3CD O00329 2/20 0.33
ADH4 P08319 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2453051 0.82
SCHEMBL27719489 0.79
SCHEMBL3956369 0.77
SCHEMBL18570188 0.75 ADH1A (0.54) ADH1AADH1CADH4
SCHEMBL528874 0.75 ADH1A (0.54) ADH1AADH1CADH4
SCHEMBL3949145 0.73 ADH1A (0.61) ADH1AADH1CPIK3CDADH4
SCHEMBL27510273 0.71 PIK3CD (0.36) ADH1AADH1CPIK3CDADH4
SCHEMBL772050 0.71 ADH1A (0.60) ADH1AADH1CPIK3CDADH4
SCHEMBL18493881 0.71 PIK3CD (0.37) PIK3CD
SCHEMBL29113665 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103153945-B 1-oximino-3-phenyl-propanes HOFFMAN-LA ROCHE LTD. (CH) 2016-03-02 CN disclosed