Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | PRNP | P04156 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835430 | 0.82 | PDE4A (0.45) | MAOAMAOBMETAP1RXFP1PRNP | |
| SCHEMBL13158216 | 0.81 | MAOA (0.47) | MAOAMAOBMETAP1TSHRPDE4A | |
| SCHEMBL11735484 | 0.78 | NPSR1 (0.46) | MAOAMAOBNPSR1RXFP1PRNP | |
| SCHEMBL13548854 | 0.78 | GPR3 (0.55) | NPSR1RXFP1PRNPTSHRUSP2 | |
| SCHEMBL19685360 | 0.77 | PRNP (0.48) | NPSR1RXFP1PRNPTSHRUSP2 | |
| SCHEMBL4753647 | 0.77 | DCPS (0.57) | MAOANPSR1RXFP1PRNPTSHR | |
| SCHEMBL31391449 | 0.77 | RXFP1 (0.44) | MAOAMAOBNPSR1RXFP1PRNP | |
| SCHEMBL20152506 | 0.76 | ADORA2A (0.55) | NPSR1ALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL856788 | 0.75 | TDP1 (0.54) | MAOAMAOBMETAP1NPSR1RXFP1 | |
| SCHEMBL29461212 | 0.75 | TDP1 (0.54) | MAOAMAOBMETAP1NPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009029617-A1 | DIARYLAMINE-SUBSTITUTED QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS | KALYPSYS, INC. (US) | 2009-03-05 | — | — | WO | disclosed |