Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949506 | 0.89 | ALDH1A1 (0.35) | GNAO1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3947080 | 0.85 | KEAP1 (0.32) | GNAO1ALDH1A1KEAP1SMN1; SMN2 | |
| SCHEMBL3954983 | 0.85 | KEAP1 (0.32) | ALDH1A1KEAP1SMN1; SMN2 | |
| SCHEMBL3947084 | 0.82 | CARM1 (0.41) | CHRM2CHRM1 | |
| SCHEMBL3957642 | 0.80 | PAOX (0.35) | GNAO1CHRM2CHRM1ALDH1A1KEAP1 | |
| SCHEMBL3949679 | 0.79 | CHRM5 (0.38) | GNAO1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3949683 | 0.79 | CHRM1 (0.33) | GNAO1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3946705 | 0.79 | KEAP1 (0.32) | ALDH1A1KEAP1SMN1; SMN2 | |
| SCHEMBL3944903 | 0.79 | S1PR5 (0.32) | ALDH1A1KEAP1SMN1; SMN2 | |
| SCHEMBL3950127 | 0.78 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024825-A1 | 2-PYRAZINYLBENZIMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-02-26 | — | — | WO | disclosed |