Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29504667 | 0.82 | — | — | |
| SCHEMBL181102 | 0.82 | — | — | |
| SCHEMBL3945936 | 0.75 | KDM4E (0.38) | ALDH1A1 | |
| SCHEMBL17688642 | 0.70 | SLC6A4 (0.36) | — | |
| SCHEMBL4212545 | 0.70 | MAOB (0.42) | ALDH1A1 | |
| SCHEMBL29488699 | 0.70 | SLC6A4 (0.36) | — | |
| Hexane SCHEMBL28095543 | 0.67 | RAB9A (0.49) | ALDH1A1 | |
| SCHEMBL19932456 | 0.67 | — | — | |
| SCHEMBL13430115 | 0.66 | CHRNB2 (0.35) | — | |
| SCHEMBL19434945 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049521-A2 | NOVEL PYRIDAZINE DERIVATIVES | Syngeta Participations AG (CH) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008009405-A2 | NOVEL PYRIDAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-24 | — | — | WO | disclosed |