Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3608608 | 0.88 | ADORA3 (0.40) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL3950147 | 0.75 | GABRA5 (0.30) | ALDH1A1 | |
| SCHEMBL2656296 | 0.72 | CYP1A2 (0.49) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8115931 | 0.71 | MAPT (0.36) | MAPTALDH1A1PKMADORA3ADORA2A | |
| SCHEMBL5371986 | 0.70 | ALDH1A1 (0.44) | KDM4EMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL4331572 | 0.70 | P4HTM (0.53) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL2643085 | 0.70 | TDP1 (0.48) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL28775127 | 0.70 | NFKB1 (0.73) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL26480953 | 0.70 | MAPT (0.48) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL13341653 | 0.70 | ALDH1A1 (0.44) | KDM4EMAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049521-A2 | NOVEL PYRIDAZINE DERIVATIVES | Syngeta Participations AG (CH) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008009405-A2 | NOVEL PYRIDAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-24 | — | — | WO | disclosed |