SCHEMBL3950195

SCHEMBL3950195

C=C(C)C(=O)ON(CC)C(=O)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.47
KMT2A Q03164 4/20 0.44
MEN1 O00255 2/20 0.44
ATM Q13315 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
NPSR1 Q6W5P4 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
ALDH1A1 P00352 3/20 0.39
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
HSD17B10 Q99714 1/20 0.38
PKM P14618 1/20 0.38
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10527061 0.86 KMT2A (0.45) ELANEKMT2AMEN1L3MBTL1TDP1
SCHEMBL3951688 0.79 THRB (0.44) KMT2AMEN1ATML3MBTL1TDP1
Propane SCHEMBL6908233 0.77 ELANE (0.67) ELANEKMT2AATML3MBTL1TDP1
Alcohol SCHEMBL22362243 0.76 ELANE (0.65) ELANEKMT2AATML3MBTL1TDP1
Benzene SCHEMBL28301757 0.75 ELANE (0.73) ELANEKMT2AATML3MBTL1TDP1
Benzene SCHEMBL27862765 0.75 ELANE (0.73) ELANEKMT2AATML3MBTL1TDP1
SCHEMBL15058 0.75 ELANE (0.73) ELANEKMT2AATML3MBTL1TDP1
SCHEMBL87437 0.75 ELANE (0.73) ELANEKMT2AATML3MBTL1TDP1
Alcohol SCHEMBL29060500 0.74 ELANE (0.63) ELANEKMT2AATML3MBTL1TDP1
SCHEMBL8679689 0.74 THRB (0.44) KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7498394-B2 (Meth)acrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2009-03-03 US disclosed
US-20060252900-A1 (Meth)arcrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained REGENTS OF THE UNIVERSITY OF COLORADO, THE 2006-11-09 US disclosed
WO-2004077511-A2 (METH)ACRYLIC AND (METH)ACRYLAMIDE MONOMERS, POLYMERIZABLE COMPOSITIONS, AND POLYMERS OBTAINED THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2004-09-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252900-A1 (Meth)arcrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained MMAB, MAT1A, MAT2A ELANE 3019/4885KMT2A 619/4885MEN1 1184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.