Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | FPR2 | P25090 | 4/20 | 0.62 |
| ▸ | PPM1B | O75688 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | FPR1 | P21462 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3493983 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1BLMLMNA | |
| SCHEMBL13311757 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1BLMLMNA | |
| SCHEMBL3496402 | 0.83 | ALDH1A1 (0.78) | ALDH1A1KMT2AMEN1BLMLMNA | |
| SCHEMBL3500228 | 0.82 | ALDH1A1 (0.76) | ALDH1A1KMT2AMEN1BLMLMNA | |
| SCHEMBL3493897 | 0.82 | KMT2A (0.76) | ALDH1A1KMT2AMEN1BLMLMNA | |
| SCHEMBL3495475 | 0.82 | ALDH1A1 (0.76) | ALDH1A1KMT2AMEN1BLMLMNA | |
| SCHEMBL3496344 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1BLMLMNA | |
| SCHEMBL3496110 | 0.81 | GAA (0.71) | ALDH1A1KMT2AMEN1BLMLMNA | |
| SCHEMBL13311427 | 0.80 | ALDH1A1 (0.72) | ALDH1A1KMT2AMEN1BLMLMNA | |
| SCHEMBL3495484 | 0.78 | LMNA (0.73) | ALDH1A1KMT2AMEN1BLMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086534-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | Genetic Technologies Limited (AU) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008058342-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | GENETIC TECHNOLOGIES LIMITED (AU) | 2008-05-22 | — | — | WO | disclosed |