Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954500 | 0.74 | RBP4 (0.39) | PDE10AALDH1A1 | |
| SCHEMBL17227450 | 0.70 | PDE10A (0.33) | PDE10A | |
| SCHEMBL7224641 | 0.69 | KDM4E (0.33) | ALDH1A1 | |
| SCHEMBL3951474 | 0.69 | GSK3A (0.36) | PDE10A | |
| SCHEMBL15767503 | 0.67 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL16283746 | 0.66 | PDE10A (0.58) | PDE10A | |
| SCHEMBL4478891 | 0.66 | ALDH1A1 (0.34) | PDE10AALDH1A1 | |
| SCHEMBL31579337 | 0.64 | CNR2 (0.34) | ALDH1A1TSHR | |
| SCHEMBL10797169 | 0.64 | RAB9A (0.64) | PDE10AALDH1A1TSHR | |
| SCHEMBL3951531 | 0.63 | KDM5B (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009029625-A1 | 4- [HETEROCYCLYL-METHYL] -8-FLUORO-QUINOLIN-2-ONES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | KALYPSYS, INC. (US) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009029625-A1 | 4- [HETEROCYCLYL-METHYL] -8-FLUORO-QUINOLIN-2-ONES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | KALYPSYS, INC. (US) | 2009-03-05 | — | — | WO | disclosed |