Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.76 |
| ▸ | THPO | P40225 | 2/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.76 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | NPY1R | P25929 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | NPY2R | P49146 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5399739 | 1.00 | CYP1A2 (0.76) | CYP1A2THPOCYP2C19ADORA2AADORA2B | |
| SCHEMBL5386836 | 0.89 | ADORA2A (0.67) | CYP1A2THPOCYP2C19ADORA2AADORA2B | |
| SCHEMBL3954518 | 0.89 | ADORA2A (0.67) | CYP1A2THPOCYP2C19ADORA2AADORA2B | |
| SCHEMBL4808305 | 0.88 | CYP1A2 (0.73) | CYP1A2THPOCYP2C19ADORA2AADORA2B | |
| SCHEMBL3952297 | 0.87 | ADORA2A (0.65) | CYP1A2THPOCYP2C19ADORA2AADORA2B | |
| SCHEMBL5380373 | 0.87 | ADORA2A (0.65) | CYP1A2THPOCYP2C19ADORA2AADORA2B | |
| SCHEMBL5392874 | 0.87 | PGK1 (0.73) | CYP1A2THPOCYP2C19ADORA2AADORA2B | |
| SCHEMBL3949633 | 0.87 | PGK1 (0.73) | CYP1A2THPOCYP2C19ADORA2AADORA2B | |
| SCHEMBL1120606 | 0.86 | CYP1A2 (0.71) | CYP1A2THPOCYP2C19ADORA2AADORA2B | |
| SCHEMBL5389974 | 0.86 | LMNA (0.73) | CYP1A2THPOCYP2C19ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156544-A1 | A1 ADENOSINE RECEPTOR AGONISTS | ELZEIN ELFATIH | 2009-06-18 | — | — | US | disclosed |
| US-7514417-B2 | A1 adenosine receptor agonists | CV THERAPEUTICS, INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-7381714-B2 | A1 adenosine receptor agonists | CV THERAPEUTICS, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| EP-1883646-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2008-02-06 | — | — | EP | disclosed |
| EP-1881991-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2008-01-30 | — | — | EP | disclosed |
| US-20060281705-A1 | A1 adenosine receptor agonists | CV THERAPEUTICS, INC. | 2006-12-14 | — | — | US | disclosed |
| US-20060276428-A1 | A1 adenosine receptor agonists | CV THERAPEUTICS, INC. | 2006-12-07 | — | — | US | disclosed |
| WO-2006125211-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2006-11-23 | — | — | WO | disclosed |
| WO-2006125190-A1 | A1 ADENOSINE RECEPTOR AGONISTS | CV THERAPEUTICS, INC. (US) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156544-A1 | A1 ADENOSINE RECEPTOR AGONISTS | ADORA1, ADORA2A, ADORA3 | CYP1A2 358/4885THPO 2235/4885CYP2C19 768/4885 |
| US-20060281705-A1 | A1 adenosine receptor agonists | ADORA1, ADORA2A, ADORA3 | CYP1A2 358/4885THPO 2235/4885CYP2C19 768/4885 |
| US-20060276428-A1 | A1 adenosine receptor agonists | ADORA1, ADORA2A, ADORA3 | CYP1A2 358/4885THPO 2235/4885CYP2C19 768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.