Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954698 | 1.00 | KDM4E (0.59) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2604953 | 0.83 | BACE1 (0.61) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2604931 | 0.81 | CYP1A2 (0.61) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13583515 | 0.80 | KDM4E (0.65) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11670985 | 0.80 | KDM4E (0.56) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11670988 | 0.80 | KDM4E (0.56) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2604947 | 0.79 | KDM4E (0.55) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7009887 | 0.79 | KDM4E (0.55) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2604951 | 0.79 | CYP1A2 (0.55) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7009884 | 0.79 | KDM4E (0.55) | KDM4EHPGDCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025118034-A1 | COMPOUNDS ACTIVE AT THE SEROTONERGIC 5-HT2A RECEPTOR | Psylo Pty Ltd (AU) | 2025-06-12 | — | — | WO | disclosed |
| US-7538123-B2 | Indole derivative having piperidine ring | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-05-26 | — | — | US | disclosed |
| US-7538123-B2 | Indole derivative having piperidine ring | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-05-26 | — | — | US | disclosed |
| US-20070219179-A1 | Indole Derivative Having Piperidine Ring | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070219179-A1 | Indole Derivative Having Piperidine Ring | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1757599-A1 | INDOLE DERIVATIVES HAVING PIPERIDINE RINGS | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |
| EP-1757599-A1 | INDOLE DERIVATIVES HAVING PIPERIDINE RINGS | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |
| US-20050256103-A1 | Indole derivative having piperidine ring | EISAI CO., LTD. | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219179-A1 | Indole Derivative Having Piperidine Ring | HTR5A, HTR2C, HTR1A | KDM4E 1505/4885HPGD 1616/4885CYP1A2 564/4885 |
| US-20050256103-A1 | Indole derivative having piperidine ring | HTR5A, HTR2C, HTR1A | KDM4E 1558/4885HPGD 1202/4885CYP1A2 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.