Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 16/20 | 0.59 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.58 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232663 | 0.86 | HSD11B1 (0.78) | HSD11B1HSD11B2 | |
| SCHEMBL6336789 | 0.85 | HSD11B1 (0.79) | HSD11B1HSD11B2 | |
| SCHEMBL4215598 | 0.85 | HSD11B1 (0.57) | HSD11B1HSD11B2PANK3 | |
| SCHEMBL15899769 | 0.84 | HSD11B1 (0.60) | HSD11B1HSD11B2 | |
| SCHEMBL2053330 | 0.83 | HSD11B1 (0.54) | HSD11B1HSD11B2 | |
| SCHEMBL3946283 | 0.81 | HSD11B1 (0.46) | HSD11B1HSD11B2 | |
| SCHEMBL6335915 | 0.80 | HSD11B1 (0.59) | HSD11B1HSD11B2PANK3CNR2DRD2 | |
| SCHEMBL6335911 | 0.80 | HSD11B1 (0.73) | HSD11B1DRD2 | |
| SCHEMBL3951382 | 0.76 | HSD11B1 (0.74) | HSD11B1HSD11B2 | |
| SCHEMBL3954281 | 0.75 | DRD2 (0.46) | HSD11B1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026422-A2 | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ABBOTT LABORATORIES (US) | 2009-02-26 | — | — | WO | claimed |