Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724575 | 1.00 | TRPM8 (0.60) | TRPM8EPHX1TRPA1P2RX4ALDH1A1 | |
| SCHEMBL724576 | 1.00 | TRPM8 (0.60) | TRPM8EPHX1TRPA1P2RX4ALDH1A1 | |
| SCHEMBL720504 | 0.93 | TRPM8 (0.57) | TRPM8EPHX1TRPA1TRPV1 | |
| SCHEMBL720505 | 0.93 | TRPM8 (0.57) | TRPM8EPHX1TRPA1TRPV1 | |
| SCHEMBL18541154 | 0.91 | TRPM8 (0.71) | TRPM8EPHX1TRPA1TRPV1MAPT | |
| SCHEMBL722923 | 0.91 | TRPM8 (0.71) | TRPM8EPHX1TRPA1TRPV1MAPT | |
| SCHEMBL722922 | 0.91 | TRPM8 (0.71) | TRPM8EPHX1TRPA1TRPV1MAPT | |
| SCHEMBL1115691 | 0.91 | TRPM8 (0.71) | TRPM8EPHX1TRPA1TRPV1MAPT | |
| SCHEMBL358358 | 0.91 | TRPM8 (0.71) | TRPM8EPHX1TRPA1TRPV1MAPT | |
| SCHEMBL31685892 | 0.91 | TRPM8 (0.71) | TRPM8EPHX1TRPA1TRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871738-B1 | N-ALKYLCARBONYL-AMINO ACID ESTER AND N-ALKYLCARBONYL-AMINO LACTONE COMPOUNDS AND THEIR USE | WEI EDWARD T (US) | 2009-07-15 | — | — | EP | claimed |